Best GLP-1 Medications for 2026

Weight-loss injections

Weight-loss injections are rapidly gaining popularity, especially among individuals who have found traditional weight loss methods unsuccessful. As of 2024, an estimated 15.5 million people have turned to injectable weight loss medications.¹

On average, injectable medications lead to more weight loss than oral medications or diet and exercise alone.² They work alongside natural body processes to support weight loss by addressing common challenges including appetite, metabolism, and fat absorption.

How weight-loss injections work

For some people, hormonal imbalances cause increased hunger and cravings, making weight loss more difficult. These treatments are approved for people with obesity and others who haven’t been able to lose weight with diet and exercise alone.

Weight-loss injections can help reduce improper hunger cues, increase calorie burn, and prevent fat absorption, depending on the specific treatment.

Here’s how each type generally works:

• Appetite control: injections can mimic hormones that signal fullness, helping to reduce calorie intake without constant hunger signals.
• Metabolism boost: injections can help the body burn calories more efficiently by increasing metabolic rate, making the body use more energy even at rest.
• Fat absorption reduction: injections can block the absorption of fat, meaning less fat is absorbed from food.

Types of weight-loss injection medications

Weight-loss injection pens

Many weight-loss injections now come in the form of easy-to-use pens. These are pre-dosed for simple, at-home self-administering with minimal discomfort.

Injectable diabetes medication

Some diabetes medications that manage blood sugar have also proven to aid in significant weight loss. With doctor support, they can be a great option for individuals managing weight and diabetes at the same time.

Benefits of weight-loss injections

• Fast results (within a few weeks,³ especially when paired with lifestyle changes).
• Convenient at-home doses.
• Reduced risk of high blood pressure, stroke, and diabetes.⁴
• A proven method that works when other treatments (diet, exercise, pills) fail.

Pro tip: If other methods have stalled, injections can offer real, visible results. They are most effective when paired with healthy lifestyle habits.

How to take weight-loss injections

Typically, weight-loss injections are taken once daily or weekly, depending on the specific medication. Following the prescribed schedule is important for the injections to be effective.

• Daily injections (less common): often taken in the morning to help curb hunger and increase energy levels throughout the day.
• Weekly injections (more common): long-lasting and typically work over time to adjust appetite and metabolism, offering a more hands-off approach.

Most weight-loss injections are subcutaneous, meaning they are injected just under the skin. The process is designed to be as simple as possible, with minimal discomfort. The injection area should be rotated with each dose to avoid irritation.

Common areas for administering these injections include:

• Abdomen (belly)
• Upper thigh
• Upper arm

Expected weight loss from injections

Results can vary from person to person, but many patients begin to see weight loss within a few weeks of starting injections. On average, people may lose 1–2 pounds per week.³

Slow, steady weight loss over time is typical, with the most significant weight loss occurring around three to six months after treatment begins.

How to get weight-loss injections online

Many companies now offer online consultations to make accessing weight-loss injections easier. Patients can speak with a licensed professional through a virtual visit, get a prescription, and have the medication shipped directly to their home. It’s a convenient option for those who prefer to manage their health privately and efficiently.

Are weight-loss injections right for you?

If you’ve tried traditional methods like diet and exercise without success, weight-loss injections might be a good fit. Your general practitioner or online providers can help you learn if injections are appropriate for your health needs and lifestyle goals.

Ready to get started? See our list of the best companies offering weight-loss injections, compare company reviews, and view pricing to find the treatment option that’s right for you and your lifestyle goals.